Trusted by IBM · World Bank · Wells FargoTrusted by IBM · World Bank · Wells Fargo · Washington Business Journal
The Great
Business
Rewiring™
Seema Alexander helps CEOs, founders and business leaders rethink, reimagine and rewire their businesses for the AI era.
Trusted by 50+ global organizations
Keynotes · Workshops · Summits · Executive Labs · Trainings
Keynote Speaker
Founder · Disruptive AI
Rethink. Reimagine. Rewire for the AI era
Traditional business × AI-native thinking
Twenty-five years of running real businesses — now helping leaders rebuild them for an intelligent world.
The Truth
About AI
AI won't disrupt your business. Incremental thinking will.
This isn't an either/or moment. It's a yes—and redesign moment.
KEYNOTE
Signature Keynote
The Great Business
Rewiring™
Why AI Is 10x Bigger Than the Internet
A strategic, practical, and tactical keynote that changes mindsets around AI. Tailored for executive teams, company-wide town halls, and women leaders — the same framing, customized by industry, company, and audience.
Book This KeynoteThe AI Leadership Shift Framework
Rethink. Reimagine.
Rewire.
A three-phase framework for leaders ready to transform their business for the AI era.
Rethink
Gain AI fluency to challenge legacy assumptions. Understand what AI changes about your industry, customers, and competitive landscape.
Reimagine
Design bold new possibilities. Envision how AI can create new value, experiences, and business models.
Rewire
Implement with precision. Embed AI into strategy, operations, and culture for sustainable transformation.
Speaking & Workshops
Keynotes & Workshops
High-impact keynotes and interactive workshops that help organizations understand The Great Business Rewiring™ and build AI-native capability at every level.
Keynote Speaking
High-impact presentations that help organizations understand The Great Business Rewiring™ and what AI means for their industry.
Perfect For
Conferences, summits, leadership offsites, and industry events.
Executive Strategy Workshops
Interactive sessions for executive teams to identify opportunities, prioritize initiatives, and develop an AI-native operating strategy. Customized by industry and/or business segment.
Perfect For
C-suites and leadership teams shaping enterprise AI strategy.
Leadership & Management Workshops
Equip directors and managers with the mindset, frameworks, and practical tools to lead teams through AI transformation.
Perfect For
Director- and manager-level leaders driving operational change.
Employee AI Fluency Workshops
Hands-on sessions that build confidence, practical skills, and AI-native thinking across the workforce.
Perfect For
Company-wide rollouts, department upskilling, and all-hands learning days.
Every experience can be customized for enterprises, companies, trade associations, universities, and non-profit organizations.
Who She Speaks With
Five Audiences. Distinct Conversations.
Different keynotes, different stakes. Every discussion is shaped around the people in the room and the decisions they need to make next.
For CEOs, C-Suite & Boards
The Great Business Rewiring™: Why AI Is 10x Bigger Than the Internet
Keynotes and workshops for executive offsites, board strategy sessions, and C-suite AI transformation programs. Discussions center on redesigning established businesses, operating models, and strategic priorities.
Executive workshopsFor Founders
Most AI Startups Will Fail. How to Build One That Doesn't.
A founder-focused keynote for entrepreneur summits, accelerators, and startup communities. Discussions center on AI-native business models, proprietary intelligence, distribution, and building lasting competitive advantage.
Founder keynoteFor Conferences
Top AI keynote for conferences, trade associations, industry summits, leadership events, and entrepreneur summits.
See the keynotesFor Employees
AI fluency keynotes and workshops for town halls, department trainings, and company-wide learning days.
Employee programsFor Women Leaders
AI futurist keynote for women's leadership conferences, ERGs, and executive summits.
Plan your session2026 Speaker Guide
Best AI Keynote Speakers 2026 — Where Seema Fits
Today's AI keynote speakers generally focus on one of three areas: the technology behind AI, the ethics and governance of AI, or the business transformation AI makes possible.
Seema Alexander specializes in the third.
Through her signature framework, The Great Business Rewiring™, she helps CEOs, founders, and executive teams understand how AI is changing how organizations operate, compete, innovate, and create value.
If your next event needs a top AI keynote speaker who can move a room of CEOs, boards, or executive teams from AI curiosity to strategic conviction — without tool demos, prompt clinics, or recycled trend decks — Seema is on the shortlist.
“We invited Seema to give our Alliance of CEOs community a perspective on the current state of AI in the mid-market. She did an excellent job moving the conversation beyond tools and productivity and helping our CEOs think more strategically about what she calls The Great Business Rewiring™: how AI is changing the way companies operate, compete and create value. She sparked a lively, substantive discussion around operating models, data, decision-making and the competitive implications of AI. The feedback from our members was excellent. Seema brings a real ability to engage an experienced executive audience.”
Paul Witkay
Founder & CEO, Alliance of Chief Executives
"In an environment that's flooded with news and opinions on AI, Seema breaks through the noise with insights and forecasts that bring intelligence and theory to the conversation. She is an expert in this space, and with experience guiding both AI start-ups and large corporates, she brings an invaluable perspective on the value of innovation by challenging what we think we know about AI."
Katy Redmond, MCR
Senior Managing Director, JLL
"It was a thought provoking and inspiring dialogue that sparked new ideas and ways of leveraging AI in our daily work. Seema is extraordinary and we so appreciate her spending the evening with us."
Kimberly Sullivan
Principal & Co-Managing Director, Gensler | DC Office
"I witnessed firsthand how Seema transformed her industry knowledge into living examples, breaking down complex AI concepts into practical and digestible insights that resonated across various industries. Her presentation was exceptional - relatable, deeply knowledgeable, and offering a unique perspective from the business side. I highly recommend Seema to any organization looking to explore the future of business, work, and AI through a thoughtful and innovative lens."
Ziqi Li
Program Coordinator, Global Engagement - World Trade Center Institute
Experience
Fortune 500 Executive,
Ecosystem Builder to Tech Founder
CEO + Founder of Disruptive AI, an AI strategy, product, and venture studio. Host of the AI CEO Podcast. Creator of AI BusinessCon.
Former Co-chair of DC Startup + Tech Week. Founding Member, Futurist Council for AI and the Future of Work (JFF Labs).
Former Fortune 500 executive turned serial entrepreneur who has guided hundreds of companies through transformation.
What I Do
Five Pillars
Venture Studio
Building and partnering in accelerating AI innovation to market
Keynote Speaker
Signature keynote 'Why AI Is Bigger Than the Internet' delivered worldwide
The AI CEO Podcast
Host — the layman business × AI podcast for execs, founders & operators
AI BusinessCon
Creator of the world's 1st business rewiring conference — March 2–3, 2027 in the Washington, DC metro area. Registration open
5%
AI BusinessCon · March 2–3, 2027 · Washington, DC Metro · Registration Open
Only 5% of leaders get it. This conference fixes that.
On Stage
The Energy
FAQ
Frequently Asked Questions
BOOK NOW
Ready?
Inspire Your
Audience
Book Seema for your next conference, corporate event, or executive briefing — and give your audience a real, practical understanding of AI × business that inspires action, creates urgency, and replaces fear with clarity.
Get in Touch